Replaces Prod. #: ALX-270-087
KT5823 is a derivative of K-252a and is a selective, cell permeable, inhibitor of PKG (Ki=0.234 µM). Ki’s for PKA =4μM and for MLCK=>10μM.
Product Details
| Formula: | C29H25N3O5 |
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| MW: | 495.5 |
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| CAS: | 126643-37-6 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | White solid. |
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| Solubility: | Soluble in DMSO (20mg/ml), dimethyl formamide (20mg/ml) and ethyl acetate (5mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Use/Stability: | Store, as supplied, at 4°C for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases: H. Kase, et al.; Biochem. Biophys. Res. Commun.
142, 436 (1987),
Abstract;
