Major metabolite of debrisoquin. Useful indicator for cytochrome P-450 polymorphism. For analytical methods.
Product Details
| Alternative Name: | Ro 37594 |
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| MW: | 191.2 |
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| CAS: | 59333-79-8 |
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| Purity: | ≥99% |
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| Appearance: | White solid. |
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| Solubility: | Soluble in 1M HCl. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Debrisoquine 4-monooxygenase and bufuralol 1'-monooxygenase activities in bovine and rabbit tissues: Y. Matsuo, et al.; Biochem. Pharmacol.
43, 1911 (1992),
Abstract;
Determination of debrisoquine and metabolites in human urine by gas chromatography-mass spectrometry: L. Daumas, et al.; J. Chromatography
570, 89 (1991),
Abstract;
Debrisoquine metabolism and genetic predisposition to lung cancer: M. R. Law, et al.; Brit. J. Cancer.
59, 686 (1989),
Abstract;
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The assay of fentanyl and its metabolites in plasma of patients using gas chromatography with alkali flame ionisation detection and gas chromatography-mass spectrometry: H. Van. Rooy, et al.; J. Chromatography
223, 85 (1981),
Abstract;
A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population: D. A. Evans, et al.; J. Med. Genet.
17, 102 (1980),
Abstract;
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The metabolism of [14C]-debrisoquine in man: J. R. Idle, et al.; Br. J. Clin. Pharmacol.
7, 257 (1979),
Abstract;
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