Replaces Prod. #: ALX-270-039
Inhibitor of cAMP- and cGMP-dependent protein kinase (PKA, Ki=4.3µM and PKG, Ki=3.8µM), protein kinase C (PKC, Ki=47µM), casein kinase I and II, and myosin light chain kinase (MLCK, Ki=7.4µM).
Product Details
| Formula: | C12H13ClN2O2S . HCl |
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| MW: | 284.8 . 36.5 |
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| CAS: | 78957-85-4 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in water (50mg/ml), DMSO (50mg/ml) or 100% ethanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Technical Info/Product Notes: | Note: Product is not sterile. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways: J. Midkiff, et al.; PLoS One
6, e25395 (2011),
Abstract;
Full Text
Naphthalenesulfonamides as calmodulin antagonists and protein kinase inhibitors: M. Inagaki, et al.; Mol. Pharmacol.
29, 577 (1986),
Abstract;
