Major metabolite of vitamin D3. Mediates calcium and phosphorous homeostasis. Inhibits 1α,25-dihydroxyvitamin D3 and testosterone potentiation of calcium channels in osteosarcoma cells.
Product Details
| Formula: | C27H44O3 |
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| MW: | 416.6 |
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| CAS: | 55721-11-4 |
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| Formulation: | White solid dissolved in ethanol (50µg/50µl). |
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| Purity: | ≥98% (TLC) |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -80°C |
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| Use/Stability: | Store, as supplied, at -80°C for up to 1 year. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
24R,25-(OH)2 vitamin D3 inhibits 1alpha,25-(OH)2 vitamin D3 and testosterone potentiation of calcium channels in osteosarcoma cells: K. Takeuchi, et al.; J. Biol. Chem.
271, 33335 (1996),
Abstract;
24R,25-Dihydroxyvitamin D3 and 1 alpha,25-dihydroxyvitamin D3 are both indispensable for calcium and phosphorus homeostasis: A. W. Norman, et al.; Life Sci.
27, 229 (1980),
Abstract;
