A QUANTIZYME® Assay System. The MMP-12 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-12 (MMP-12, macrophage elastase, metalloelastase) using a thiopeptide as a chromogenic substrate. The assays are performed in a convenient 96-well plate format. Included are active enzyme, assay buffer, a prototypic control inhibitor (NNGH), and a detailed instruction booklet.
Product Details
| Alternative Name: | Metalloelastase, Macrophage elastase |
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| Applications: | Colorimetric detection, HTS
Activity assay
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Contents: | MMP-12 enzyme (human) (recombinant), substrate, inhibitor, assay buffer, 96-well microplate. |
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| UniProt ID: | P39900 |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Early Matrix Metalloproteinase-12 Inhibition Worsens Post-Myocardial Infarction Cardiac Dysfunction by Delaying Inflammation Resolution: R.P. Iyer, et al.; Int. J. Cardiol.
185, 198 (2015),
Application(s): Assay using mouse plasma,
Abstract;
