Product Details
| Clone: | 1G11 |
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| Host: | Rat |
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| Isotype: | IgG1 |
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| Immunogen: | Recombinant human CD83 (extracellular domain). |
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| UniProt ID: | Q01151 |
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| Species reactivity: | Human
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| Specificity: | The binding affinity strongly increases after deglycosylation of mature DC. |
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| Applications: | Flow Cytometry, WB
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| Application Notes: | NOT inhibitory to DC mediated T cell stimulation in mixed lymphocyte reactions. |
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| Purity Detail: | Protein G-affinity purified. |
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| Formulation: | Liquid. In PBS containing 0.01% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Overexpression, purification, and biochemical characterization of the extracellular human CD83 domain and generation of monoclonal antibodies: M. Lechmann, et al.; Protein Exp. Purif.
24, 445 (2002),
Abstract;
The extracellular domain of CD83 inhibits dendritic cell-mediated T cell stimulation and binds to a ligand on dendritic cells: M. Lechmann, et al.; J. Exp. Med.
194, 1813 (2001),
Abstract;
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