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CD54 (human) (domain D1) monoclonal antibody (RR1/1)

 
ALX-805-016-C050 50 µg Purified 391.00 USD
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Product Details

Alternative Name:ICAM-1, Intercellular adhesion molecule-1
 
Clone:RR1/1
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Human CD54 (ICAM-1).
 
UniProt ID:P05362
 
Species reactivity:Human
 
Specificity:Recognizes the D1 domain of CD54.
 
Applications:ELISA, Flow Cytometry, IHC (FS), WB, FUNC
 
Recommended Dilutions/Conditions:Flow Cytometry (suitable as primary antibody in staining for FACS analysis)
Immunohistochemistry (stains aceton-fixed cryostat sections or cell smears. Alkaline phosphatase-anti-alkaline phosphatase (APAAP) procedure, peroxidase anti-peroxidase (PAP) procedure or the three stage immunoperoxidase technique are recommended; use at a concentration of 0.5-1.25µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~90kDa by Western blot.
Functional Application: blocks adhesion of leukocytes to endothelial cells.
 
Formulation:Liquid. In PBS, pH 7.2-7.4.
 
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
 
Shipping:Blue Ice
 
Long Term Storage:+4°C
 
Regulatory Status:RUO - Research Use Only
 

Product Literature References

CD13 is a novel mediator of monocytic/endothelial cell adhesion: P. Mina-Osorio; J. Leukoc. Biol. 84, 448 (2008), Abstract; Full Text

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