| Alternative Name: | TRAIL receptor 1, Apo-2, CD261, DR4, Death receptor 4, TNFRSF 10A, TNF-related apoptosis-inducing ligand receptor 1, Tumor necrosis factor receptor superfamily member 10A |
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| Clone: | DJR1 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Recombinant human TRAIL-R1 extracellular domain IgG1 Fc fusion protein. |
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| UniProt ID: | O00220 |
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| GenBank ID: | U90875 |
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| Gene/Protein Identifier: | 8798 (Entrez GeneID) |
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| Species reactivity: | Human
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| Applications: | Flow Cytometry, WB
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| Purity Detail: | Affinity purified. |
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| Formulation: | Liquid. In PBS, pH 7.2, containing 0.09% sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | DR4 is 56kDa member 10A of the TNFR superfamily (TNFRSF10A), also known as TRAIL-R1, Apo-2, and CD261. It is expressed at low levels by activated T cells and some tumors. After TRAIL engagement, DR4 (TRAIL-R1), through activation of NF-κB, induces apoptosis in the TRAIL ligated cell. |
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| Regulatory Status: | RUO - Research Use Only |
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