Product Details
Alternative Name: | ODF, TRANCE, OPGL, TNFSF 11, CD254 |
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Clone: | Ranky-1 |
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Host: | Rat |
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Isotype: | IgG1 |
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Immunogen: | Recombinant human soluble RANKL extracellular domain (aa 151-316) (Prod. No. ALX-522-012). |
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UniProt ID: | O14788 |
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Source: | Purified from concentrated hybridoma tissue culture supernatant. |
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Species reactivity: | Human
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Applications: | ELISA, IHC (PS), WB
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Recommended Dilutions/Conditions: | ELISA (capture) Western Blot (1:1,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Does not work for Flow Cytometry or Immunoprecipitation. Does not block RANK-RANKL interaction. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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Use/Stability: | Stable for at least 1 year after receipt when stored at -20°C. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Short Term Storage: | +4°C |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Figure: Immunohistochemical staining of endogenous human RANKL in different human tissues (paraffin sections) using MAb to RANKL (human)(Ranky-1) (Prod. No.
ALX-804-830).
Method: Different human tissues (A: Duodenum; B: Small intestine) were stained with MAb to RANKL (human) (Ranky-1) by standard immunohistochemistry.
Pictures courtesy of Human Protein Atlas (www.proteinatlas.org)."
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General Literature References
The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling: S. Theoleyre, et al.; Cytokine Growth Factor Rev.
15, 457 (2004),
Abstract;