Product Details
| Alternative Name: | BCL2L1 |
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| Clone: | 1C2 |
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| Host: | Rat |
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| Isotype: | IgG2a κ |
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| Immunogen: | Recombinant mouse Bcl-XL (aa 1-209). |
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| UniProt ID: | Q64373 |
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| Species reactivity: | Human, Mouse
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| Applications: | ELISA, Flow Cytometry, IP, WB
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| Purity Detail: | Protein G-affinity purified. |
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| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak: R.T. Uren, et al.; J. Cell Biol.
177, 277 (2007),
Abstract;
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins: S.N. Willis, et al.; Genes Dev.
19, 1294 (2005),
Abstract;
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