Product Details
| Alternative Name: | TLR5, Toll/Interleukin-1 receptor-like gene 3, TIL3 |
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| Clone: | 85B152.5 |
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| Host: | Mouse |
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| Isotype: | IgG2a |
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| Immunogen: | Synthetic peptide corresponding to a portion of human TLR5 (Toll-like receptor 5). |
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| UniProt ID: | O60602 |
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| Species reactivity: | Human, Mouse
Dog
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| Applications: | Flow Cytometry
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| Application Notes: | Flow Cytometry: Suitable for cell surface and intracellular FC. |
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| Positive Control: | Ramos cells can be used as positive control. |
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| Purity Detail: | Protein G-affinity purified. |
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| Formulation: | Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide. |
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| Use/Stability: | Stable for 6 months when stored at +4°C. |
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| Handling: | Do not freeze. Protect from light. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Figure: Intracellular FACS analysis of TLR5 in 10
6 ThP1 cells using 5µg of MAb to Toll-like Receptor 5 (85B152.5) (R-PE) (Prod. No.
ALX-804-597R). The shaded histogram represents ThP1 cells alone, green represents isotype control, and pink represents TLR5 antibody."
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Product Literature References
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils: C.K. Wong, et al.; Am. J. Respir. Cell Mol. Biol.
37, 85 (2007),
Abstract;
Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk: E. LeBouder, et al.; J. Immunol.
176, 3742 (2006),
Abstract;
Full Text
Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis: A. Mansson, et al.; Respir. Res.
7, 36 (2006),
Abstract;
Full Text
Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells: N.K. Crellin, et al.; J. Immunol.
175, 8051 (2005),
Abstract;
Full Text
