Product Details
| Alternative Name: | Lipopolysaccharide binding protein |
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| Clone: | biG 33 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Recombinant mouse LBP (lipopolysaccharide binding protein) (in LBP knockout mouse). |
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| UniProt ID: | Q61805 |
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| Species reactivity: | Mouse
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| Crossreactivity: | Cross-reacts weakly with rat LBP. |
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| Applications: | ELISA, WB, FUNC
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| Recommended Dilutions/Conditions: | ELISA, Western Blot, Functional Application (Inhibits binding of LPS to membrane bound CD14) |
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| Application Notes: | Functional Application: inhibits binding of LPS to membrane bound CD14. |
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| Purity Detail: | Protein-G affinity purified. |
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| Endotoxin Content: | <0.1ng/ml (LAL-test Charles River) |
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| Formulation: | Lyophilized. Contains PBS. |
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| Reconstitution: | Reconstitute with 40µl distilled water. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Technical Info/Product Notes: | Binding titer at mouse LBP-ELISA: 1:50'000.
Inhibits LPS-binding (0.5µg/ml) to CD14+ CHO cells (2x106/ml) up to 1:1'000, total inhibition is 1:5. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Implications for a general role of LPS-binding proteins (CD14, LBP) in combating bacterial infections: C. Schütt, et al.; J. Endotoxin Res.
5, 75 (1999),
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