Product Details
| Alternative Name: | Bcl-2-modifying factor |
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| Clone: | 12E10 |
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| Host: | Rat |
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| Isotype: | IgG1 |
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| Immunogen: | Recombinant mouse Bmf. |
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| UniProt ID: | Q91ZE9 |
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| Species reactivity: | Human, Mouse
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| Applications: | Flow Cytometry, IP, WB
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| Application Notes: | Excellent for Flow Cytometry. |
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| Purity Detail: | Protein G-affinity purified. |
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| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic: J. Kuroda, et al.; PNAS
103, 14907 (2006),
Abstract;
Full Text
Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis: H. Puthalakath, et al.; Science
293, 1829 (2001),
Abstract;
