Product Details
Alternative Name: | Interleukin-8 receptor type A, CXC chemokine receptor 1, CXCR1, CD181 |
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Clone: | SE 2 |
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Host: | Mouse |
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Isotype: | IgG2b |
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Immunogen: | Human IL-8 (interleukin-8) receptor, type A. |
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UniProt ID: | P25024 |
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Species reactivity: | Human
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Specificity: | Recognizes purified human IL-8 receptor, type A. |
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Applications: | Flow Cytometry, IHC (FS), WB
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Recommended Dilutions/Conditions: | Flow Cytometry (10µg/ml) Immunohistochemistry (acetone fixed frozen sections) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | NOT suitable for neutralizing assay. |
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Formulation: | Liquid. Purified antibody in TRIS/glycine containing 0.05% sodium azide. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The biologic role of interleukin-8: functional analysis and expression of CXCR1 and CXCR2 on human eosinophils: H. Petering, et al.; Blood
93, 694 (1999),
Abstract;
Full Text
Chemoattractant receptors for interleukin-8 and C5a: expression on peripheral blood leukocytes and differential regulation on HL-60 and AML-193 cells by vitamin D3 and all-trans retinoic acid: S. Zahn, et al.; Eur. J. Immunol.
27, 935 (1997),
Abstract;
The CXC-chemokine neutrophil-activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2: A. Ludwig, et al.; Blood
90, 4588 (1997),
Abstract;
Full Text