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ODN 1668 (TLRGRADE®) (synthetic) (BULK)

TLR9 activator
 
ALX-746-051-M001 1 mg 706.00 USD
Do you need bulk/larger quantities?
 
For a smaller pack size, please see Prod. No. ALX-746-001.
CpG oligodeoxynucleotide (Type B) with phosphorothioate backbone. Specific ligand for mouse TLR9 (Toll-like receptor 9).

Product Details

Sequence:5’-tccatgacgttcctgatgct-3’ (lower case letters indicate phosphorothioate linkage).
 
MW:6383 (ammonium salt)
 
Source:Synthetic.
 
Quantity:157.1nmol
 
Formulation:Lyophilized. Sterile.
 
Purity Detail:Activity and endotoxin tested - TLRGRADE®.
 
Endotoxin Content:<0.002EU/µg (LAL test; BioWhittaker)
 
Reconstitution:For a 200µM stock solution, dissolve the total vial content in 786µl endotoxin-free ddWater (Prod. No. ALX-505-008) or endotoxin-free PBS (Prod. No. ALX-505-007). To obtain optimal dissolving we recommend the following procedure:
- Add 50% of the solvent and let dissolve for 10 min.
- Add remaining 50% of the solvent and mix thoroughly.
- Moderate warming may aid dissolving.
 
Shipping:Ambient Temperature
 
Long Term Storage:+4°C
 
Use/Stability:Aqueous stock solution is stable for 1 day when stored at +4°C.
 
Handling:Protect from light. For maximum product recovery after thawing, centrifuge the vial before opening the cap. After reconstitution, prepare aliquots and store at -20°C.
 
Technical Info/Product Notes:Includes 1 vial of ddWater (endotoxin-free) (Prod. No. ALX-505-008).
For the inactive control compound, please see Prod. No. ALX-746-200.
 
Regulatory Status:RUO - Research Use Only
 

Product Literature References

CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes: K. Rawat, et al.; J. Exp. Med. 220, e20222129 (2023), Abstract;

Related Products

ddWater (endotoxin-free) (sterile) 

7732-18-5 | Print as PDF
 
ALX-505-008-LD15 1.5 ml 50.00 USD
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PBS (endotoxin-free) (sterile) 

Print as PDF
 
ALX-505-007-LD15 1.5 ml 67.00 USD
 
ALX-505-007-L010 10 ml 132.00 USD
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ODN 1720 (TLRGRADE®) (synthetic) (Control) 

Negative control for ODN 1668
Synthetic. | Print as PDF
 
ALX-746-200-T100 100 tests 210.00 USD
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ODN 1668 (TLRGRADE®) (synthetic) 

TLR9 ligand
Synthetic. | Print as PDF
 
ALX-746-001-C100 100 µg 192.00 USD
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