Highly potent NMDA receptor antagonist.
Product Details
| Alternative Name: | 3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid |
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| Formula: | C8H17N2O5P |
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| MW: | 252.2 |
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| CAS: | 126453-07-4 |
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| Purity: | ≥97% (HPLC) |
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| Appearance: | White crystalline powder. |
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| Solubility: | Soluble in dilute aqueous base or water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Design and Initial Characterization of a Small Near-Infrared Fluorescent Calcium Indicator: M.E. Matlashov, et al.; Front Cell Dev Biol
10, 880107 (2022),
Abstract;
Synthesis and NMDA antagonistic properties of the enantiomers of 4-(3-phosphonopropyl)piperazine-2-carboxylic acid (CPP) and of the unsaturated analogue (E)-4-(3-posphonoprop2-enyl)piperazine-2-carboxylic acid (CPP-ene): B. Aebischer, et al.; Helv. Chim. Acta 72, 1043 (1989),
CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity: J. Davies, et al.; Brain Res.
382, 169 (1986),
Abstract;
