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TEMPONE

Spin trapping reagent
 
ALX-430-079-G001 1 g Inquire for pricing
 
ALX-430-079-M250 250 mg Inquire for pricing
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Spin trap, useful for both in vitro and in vivo experiments.

Product Details

Alternative Name:4-Oxo-2,2,6,6-tetramethylpiperidine-1-oxyl, 4-Oxo-TEMPO
 
Formula:C9H16NO2
 
MW:170.2
 
CAS:2896-70-0
 
Purity:≥98% (Assay)
 
Identity:Determined by IR.
 
Appearance:Orange crystalline powder.
 
Solubility:Soluble in acetone, DMSO, diethylether, 100% ethanol or water.
 
Shipping:Blue Ice
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
Regulatory Status:RUO - Research Use Only
 
ALX-430-079
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Product Literature References

Metabolism of the stable nitroxyl radical 4-oxo-2,2,6, 6-tetramethylpiperidine-N-oxyl (TEMPONE): C. Kroll & H.H. Borchert; Eur. J. Pharm. Sci. 8, 5 (1999), Abstract;
Characterization of the 4-oxo-2,2,6,6-tetramethylpiperidinooxy dosimeter for in situ radiolysis electron spin resonance studies: K.P. Madden; Radiat. Res. 147, 335 (1997), Abstract;
Cytotoxicity of spin trapping compounds: R.F. Haseloff, et al.; FEBS Lett. 418, 73 (1997), Abstract;
Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis: A.F. Slater, et al.; Biochem. J. 306, 771 (1995), Abstract;
Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, tempol: J.B. Mitchell, et al.; Arch. Biochem. Biophys. 289, 62 (1991), Abstract;
Biologically active metal-independent superoxide dismutase mimics: J.B. Mitchell, et al.; Biochemistry 29, 2802 (1990), Abstract;
Superoxide reaction with nitroxides: A. Samuni, et al.; Free Rad. Res. Commun. 9, 241 (1990), Abstract;
Cytotoxicity of commonly used nitroxide radical spin probes: E.G. Ankel, et al.; Life Sci. 40, 495 (1987), Abstract;

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