TEMPONE-H . hydrochloride

Spin trapping reagent



ALX-430-071-M250	250 mg	Inquire for pricing

ALX-430-071-M050	50 mg	Inquire for pricing

ALX-430-071-M010	10 mg	Inquire for pricing
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Very effective, cell permeable and non-toxic spin trap for the detection of superoxide radical and peroxynitrite.

Product Details

Alternative Name:	1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine . HCl

Formula:	C₉H₁₇NO₂ . HCl

MW:	171.2 . 36.5

CAS:	3637-11-4

Purity:	≥99% (GLC)

Appearance:	White to off-white crystalline powder.

Solubility:	Soluble in DMSO, water, methanol or 100% ethanol.

Shipping:	Blue Ice

Long Term Storage:	-20°C

Use/Stability:	Stable for at least two years after receipt when stored at -20°C.

Regulatory Status:	RUO - Research Use Only

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Product Literature References

Dynamic Wood Smoke Aerosol Toxicity during Oxidative Atmospheric Aging: S. Wang, et al.; Environ. Sci. Technol. 3, 1246 (2023), Abstract;

Biomonitoring Pilot Study in Workers from a Paints Production Plant Exposed to Pigment-Grade Titanium Dioxide (TiO2): E. Bergamaschi, et al.; Toxics 10, 171 (2022), Abstract;

Changes of physico-chemical properties of nano-biomaterials by digestion fluids affect the physiological properties of epithelial intestinal cells and barrier models: G. Antonello, et al.; Part. Fibre Toxicol. 19, 49 (2022), Abstract;

Therapeutic targeting of mitochondrial superoxide in hypertension: A.E. Dikalova, et al.; Circ. Res. 107, 106 (2010), Abstract;

Quantification of peroxynitrite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine: S. Dikalov, et al.; BBRC 230, 54 (1997), Abstract;

Quantification of superoxide radicals and peroxynitrite in vascular cells using oxidation of sterically hindered hydroxylamines and electron spin resonance: S. Dikalov, et al.; Nitric Oxide Biol. Chem. 1, 423 (1997), Abstract;

Spin trapping of superoxide radicals and peroxynitrite by 1-Hydroxy-3-carboxy-pyrrolidine and 1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine and the stability of corresponding nitroxyl radicals towards biological reductants: S. Dikalov, et al.; BBRC 231, 701 (1997), Abstract;