Ionophore antibiotic. Inhibitor of the S. cerevisiae ABC transporter Pdr5p.Inhibitor of acyl-CoA-cholesterol acyltransferase and of phosphodiesterase. Potential anticancer compound.
Product Details
Formula: | C33H57N3O9 |
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MW: | 639.8 |
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Source: | Isolated from Fusarium orthoceras var. enniatum. |
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CAS: | 917-13-5 |
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MI: | 14: 3585 |
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Purity: | ≥90% (HPLC) |
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Appearance: | White to off-white crystalline solid. |
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Solubility: | Soluble in DMSO or other organic solvents; almost insoluble in water. |
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Shipping: | Ambient Temperature |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Beauvericin and enniatin B effects on a human lymphoblastoid Jurkat T-cell model: L. Manyes, et al.; Food Chem. Toxicol.
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Abstract;
Mycotoxin occurrence on baled and pit silages collected in Co. Meath: C. McElinney, et al.; Irish J. Agr. Food. Res.
54, 87 (2015),
Application(s): Liquid chromatography tandem mass spectrometry for Mycotoxin analysis,
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Toxic indole alkaloids avrainvillamide and stephacidin B produced by a biocide tolerant indoor mold Aspergillus westerdijkiae: R. Mikkola, et al.; Toxicon.
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Application(s): Cell Culture ,
Abstract;
Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells: R. Dornetshuber, et al.; Chem. Res. Toxicol.
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Abstract;
Enniatin has a new function as an inhibitor of Pdr5p, one of the ABC transporters in Saccharomyces cerevisiae: K. Hiraga, et al.; Biochem. Biophys. Res. Commun.
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Abstract;
Interaction of cyclic peptides and depsipeptides with calmodulin: K.A. Mereish, et al.; Pept. Res.
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Abstract;
"Sandwich" complexation in cyclopeptides and its implications in membrane processes: V.T. Ivanov; Ann. N. Y. Acad. Sci.
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Abstract;
Ionophore antibiotics produced by the fungus Fusarium orthoceras var. enniatum and other Fusaria: E. Gaumann, et al.; Experientia 3, 202 (1947),