Broad-spectrum cell culture antibiotic that is nontoxic to viruses and mammalian cells at antibacterial and antimycoplasmal concentrations. Due to its extended stability and slow development of bacterial resistance, it is a useful antibiotic in long-term virus und tissue culture studies.
Product Details
| Formula: | C63H131N15O25S |
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| MW: | 1530.9 |
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| Source: | Isolated from Micromonospora sp. |
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| CAS: | 1405-41-0 |
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| MI: | 14: 4392 |
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| RTECS: | LY2625000 |
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| Appearance: | White to off-white powder. |
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| Activity: | Potency is ≥590 IU/mg (anhydrous material). |
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| Solubility: | Soluble in water; almost insoluble in alcohol or ether. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Handling: | Hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Aminoglycoside antibiotics: old drugs and new therapeutic approaches: T. Hermann; Cell. Mol. Life. Sci.
64, 1841 (2007), Review,
Abstract;
Molecular insights into aminoglycoside action and resistance: S. Magnet and J.S. Blanchard; Chem. Rev.
105, 477 (2005), Review,
Abstract;
Isolation, Purification, and Characterization of Gentamicin: J.P. Rosselet, et al.; Antimicrobial Agents Chemother. (Bethesda)
161, 14 (1963),
Abstract;
Microbiological Assay of Gentamicin: E.M. Oden, et al.; Antimicrobial Agents Chemother. (Bethesda)
161, 8 (1963),
Abstract;
Pharmacology of Gentamicin, a New Broad-Spectrum Antibiotic: J. Black, et al.; Antimicrobial Agents Chemother. (Bethesda)
161, 138 (1963),
Abstract;
