Glucoside of genistein (Prod. No. ALX-350-006) found in soy beans. Useful as a negative control for genistein and other tyrosine kinase inhibitors. Selective inhibitor of terminal deoxyribonucleotidyltransferase (TdT). Displays antioxidant and anticarcinogenic properties.
Product Details
| Alternative Name: | Genistein-7-O-glucoside |
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| Formula: | C21H20O10 |
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| MW: | 432.4 |
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| CAS: | 529-59-9 |
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| MI: | 14: 4391 |
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| RTECS: | DJ3093000 |
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| Purity: | ≥98% (HPLC, TLC) |
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| Appearance: | Off-white to light yellow powder. |
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| Solubility: | Soluble in DMSO or dilute aqueous base; insoluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells: E.J. Choi, et al.; Life Sci.
80, 1403 (2007),
Abstract;
Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells: A. Russo, et al.; J. Nutr. Biochem.
17, 103 (2006),
Abstract;
Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin: Y. Uchiyama, et al.; Biochim. Biophys. Acta
1725, 298 (2005),
Abstract;
Daidzein and genistein but not their glucosides are absorbed from the rat stomach: M.K. Piskula, et al.; FEBS Lett.
447, 287 (1999),
Abstract;
Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones: H.G. Shertzer, et al.; Chem. Biol. Interact.
123, 31 (1999),
Abstract;
Soybean isoflavones, genistein and genistin, inhibit rat myoblast proliferation, fusion and myotube protein synthesis: S. Ji, et al.; J. Nutr.
129, 1291 (1999),
Abstract;
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