Antibiotic. Inhibits protein synthesis in prokaryotes and eukaryotes. Inhibits binding of aminoacyl-tRNA to ribosomes. Used as a fluorescent Ca2+ probe.
Product Details
| Alternative Name: | Aureomycin . HCI |
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| Formula: | C22H23ClN2O8. HCl |
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| MW: | 515.4 |
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| Source: | Isolated from Streptomyces aureofaciens. |
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| CAS: | 64-72-2 |
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| MI: | 14: 2192 |
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| Purity: | ≥85% (UHPLC) |
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| Appearance: | Yellow powder. |
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| Solubility: | Soluble in 1M NaOH (50mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The effect of chlortetracycline treatment and its subsequent withdrawal on multi-resistant Salmonella enterica serovar Typhimurium DT104 and commensal Escherichia coli in the pig: A.A. Delsol, et al.; J. Appl. Microbiol.
95, 1226 (2003),
Abstract;
Chlortetracycline, oxytetracycline, and tetracycline in edible animal tissues, liquid chromatographic method: collaborative study: J.D. MacNeil, et al.; J. AOAC Int.
79, 405 (1996),
Abstract;
Effect of bile acids on intracellular calcium in isolated rat hepatocyte couplets: N. Thibault & F. Ballett; Biochem. Pharmacol.
45, 289 (1993),
Abstract;
Characterization of chlortetracycline (aureomycin) as a calcium ionophore: J.R. White & F.L. Pearce; Biochemistry
21, 6309 (1982),
Abstract;
Inhibition of thrombin-induced secretion from platelets by chlortetracycline and its analogs: E.H. Murer and E. Siojo; Thromb. Haemost.
47, 62 (1982),
Abstract;
