Bitter principle of citrus fruits. Inhibits chemically induced carcinogenesis. Inhibits HIV-1 replication. Shows antinociceptive effect. Does not possess any inherent antioxidant activity.
Product Details
Alternative Name: | Limonoic acid di-δ-lactone |
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Formula: | C26H30O8 |
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MW: | 470.5 |
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Source: | Isolated from grapefruit seed. |
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CAS: | 1180-71-8 |
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MI: | 14: 5494 |
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Purity: | ≥98% (UHPLC) |
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Appearance: | White to off-white solid. |
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Solubility: | Soluble in 100% ethanol or glacial acetic acid; slightly soluble in water. |
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Shipping: | Ambient Temperature |
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Long Term Storage: | Ambient |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside: A.P. Breksa, 3rd & G.D. Manners; J. Agric. Food Chem.
54, 3827 (2006),
Abstract;
Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells: L. Battinelli, et al.; Planta Med.
69, 910 (2003),
Abstract;
Citrus limonoids obacunone and limonin inhibit azoxymethane-induced colon carcinogenesis in rats: T. Tanaka, et al.; Biofactors
13, 213 (2000),
Abstract;
Antinociceptive and anti-inflammatory activities of limonin isolated from the fruits of Evodia rutaecarpa var. bodinieri: H. Matsuda, et al.; Planta Med.
64, 339 (1998),
Abstract;
Inhibition of Chemically Induced Carcinogenesis by Citrus Limonoids: L.K.T. Lam, et al.; ACS Symposium Series
546, 209 (1994),
Abstract;
The effect of citrus limonoids on hamster buccal pouch carcinogenesis: E.G. Miller, et al.; Carcinogenesis
10, 1535 (1989),
Abstract;
Antifeedant effects of nomilin on Spodoptera frugiperda and Trichoplusia ni under laboratory conditions: M.A. Altieri, et al.; Protect. Ecol. 6, 91 (1984),
Citrus limonoid by-products as insect control agents: J.A. Klocke & I. Kubo; Ent. Exp. & Appl.
32, 299 (1982),
Abstract;
Nomilin, a new bitter component in grapefruit juice: R.L. Rouseff; J. Agric. Food Chem.
30, 504 (1982),
Abstract;
Limonin and limonoids: chemistry, biochemistry, and juice bitterness: V.P. Maier, et al.; ACS Symposium Series
143, 63 (1980),
Abstract;