Synthetic peptide that irreversibly inhibits granzyme B activity. The inhibitor is desigend as a methyl ester to facilitate cell permeability.
Product Details
| Alternative Name: | Granzyme B inhibitor (chloromethylketone) |
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| Sequence: | Z-Ala-Ala-Asp-chloromethylketone |
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| MW: | 441.9 |
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| Concentration: | 10mM |
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| Formulation: | Liquid. In DMSO. |
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| Purity: | ≥95% (HPLC) |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB: M. Zhang, et al.; Structure
30, 685 (2022),
Abstract;
