Replaces Prod. #: BML-P446
Reversible aldehyde inhibitor of caspase-9 and related cysteine proteases. Sequence is from combinatorial experiments.
Product Details
| Alternative Name: | Caspase-9 inhibitor (aldehyde) |
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| Sequence: | Ac-Leu-Glu-His-Asp-CHO |
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| Formula: | C23H34N6O9 |
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| MW: | 538.6 |
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| Peptide Content: | 75-95% |
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| Purity: | ≥95% |
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| Appearance: | Lyophilized. |
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| Solubility: | Soluble in water or DMSO. Further dilute with buffer, pH 7.5. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Keep sealed after removing from the freezer until its temperature equilibrates with room temperature. Dissolve only amount needed at a time to avoid decomposition in solution. |
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| Handling: | Keep cool and dry. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Curcumin differentially affects cell cycle and cell death in acute and chronic myeloid leukemia cells: M. Martinez-Castillo, et al.; Oncol. Lett.
15, 6777 (2018),
Abstract;
Full Text
Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells: A.Y. Jong, et al.; J. Extracell. Vesicles
6, 1294368 (2017),
Abstract;
Full Text
Differential apoptosis-related protein expression, mitochondrial properties, proteolytic enzyme activity, and DNA fragmentation between skeletal muscles: E.M. McMillan, et al.; Am. J. Physiol. Regul. Integr. Comp. Physiol.
300, R531 (2011),
Abstract;
Full Text
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis: N.A. Thornberry et al.; J. Biol. Chem.
272, 17907 (1997),
Abstract;
