Irreversible, cell permeable inhibitor of caspase-9. The carboxyl groups are OMe ester form to enhance cell permeability. If purified enzyme is used, esterase should be added for the hydrolysis of the ester groups.
Product Details
| Alternative Name: | Caspase-9 inhibitor (fluoromethylketone) |
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| Sequence: | Z-Leu-Glu(OMe)-His-Asp(OMe)-fluoromethylketone |
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| Formula: | C32H43FN6O10 |
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| MW: | 690.7 |
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| Formulation: | TFA salt. |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | Off-white to tan solid. |
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| Solubility: | Soluble in DMSO (20mM). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stock solutions should be stored in aliquots at -20°C. |
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| Handling: | Very hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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