Irreversible, cell permeable inhibitor of caspase-1. Also inhibits caspase-4.
Product Details
| Alternative Name: | Caspase-1 inhibitor, Ac-Tyr-Val-Ala-Asp-2,6-dimethylbenzoyloxymethylketone, Ac-YVAD-AOM |
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| Sequence: | Ac-Tyr-Val-Ala-Asp-2,6-dimethylbenzoyloxymethylketone |
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| Formula: | C33H42N4O10 |
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| MW: | 654.7 |
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| Peptide Content: | 78-99% |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | White powder. |
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| Solubility: | Soluble in DMSO or methanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stock solutions should be divided into aliquots and stored at -20°C. |
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| Handling: | Keep cool and dry. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Ecto-ATPase CD39 Inactivates Isoprenoid-Derived Vγ9Vδ2 T Cell Phosphoantigens: G. Gruenbacher, et al.; Cell Rep.
16, 30728 (2016),
Application(s): Bioactivity and cell analysis,
Abstract;
Inactivation of interleukin-1 beta converting enzyme by peptide (acyloxy)methyl ketones: N.A. Thornberry, et al.; Biochemistry
33, 3934 (1994),
Abstract;
