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HSF2 monoclonal antibody (3E2)

 
ADI-SPA-960-E 100 µg 355.00 USD
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Product Details

Alternative Name:HSTF2, Heat shock factor protein 2
 
Clone:3E2
 
Host:Rat
 
Isotype:IgG
 
Immunogen:Recombinant mouse HSF2.
 
UniProt ID:P38533
 
Source:Purified from mouse ascites.
 
Species reactivity:Human, Mouse, Rat
Bovine, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Sheep
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (4µg/ml, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Western Blot (4µg/ml, colorimetric)
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:HSFs (Heat Shock family of transcription factors), which consists of HSF 1-4, bind to highly conserved Heat shock elements (HSEs) in the promoter regions of heat shock genes, ultimately regulating the expression of Heat shock proteins (Hsps). On exposure to heat shock and other stresses, HSF1 localizes within seconds to discrete nuclear granules and on recovery from stress, HSF1 rapidly dissipates from the stress granules to a diffuse nucleoplasmic distribution.
 
Regulatory Status:RUO - Research Use Only
 
HSF2 monoclonal antibody (3E2) Western blot
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HSF2 monoclonal antibody (3E2) Western blot

Product Literature References

Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition: G. Figlia, et al.; Nat. Cell Biol. 24, 1407 (2022), Abstract;

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