Alternative Name: | protein kinase C |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to a portion of human PKC. The sequence is completely conserved between the α, β, and δ isoforms of PKC. |
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UniProt ID: | P17252 (PKCalpha) |
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Source: | Purified from rabbit serum. |
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Species reactivity: | Human, Mouse, Rat Bovine, Chicken, Dog, Guinea pig, Monkey, Porcine, Rabbit, Sheep
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Applications: | IHC, IP, WB
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Recommended Dilutions/Conditions: | Immunohistochemistry (1:50) Immunoprecipitation (12.5µg/ml) Western Blot (2µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~67-83kDa by Western blot. |
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Purity Detail: | Protein A affinity purified. |
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Formulation: | Liquid. In borate buffered saline, pH 8.2. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Protein Kinase C (PKC) is a large superfamily of serine/threonine kinases that mediate essential cellular signals required for activation, proliferation, differentiation and survival. There are at least ten PKC isotypes that are closely related in structure but that have distinct patterns of tissue distribution and function. The PKC isotypes can be subdivided into three classes based on primary structure and biochemical properties. These are: classical or conventional PKC isotypes (cPKC), novel PKC isotypes (nPKC) and atypical PKC isotypes (aPKC). |
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Regulatory Status: | RUO - Research Use Only |
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