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[pThr²³²]Aurora B polyclonal antibody



ADI-KAP-CC203-D	50 µg	283.00 USD

ADI-KAP-CC203-F	200 µg	528.00 USD
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Host:	Rabbit

Immunogen:	Synthetic peptide corresponding to a portion of human Aurora B phosphorylated at Thr²³².

UniProt ID:	Q96GD4

GenBank ID:	AAH80581

Source:	Purified from rabbit serum.

Species reactivity:	Human

Crossreactivity:	Weakly cross-reacts with mouse, rat, bovine and pig Aurora B.

Applications:	IHC (PS), WB

Recommended Dilutions/Conditions:	Western Blot (1µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.

Purity Detail:	Peptide affinity purified.

Formulation:	Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.

Handling:	Avoid freeze/thaw cycles.

Shipping:	Blue Ice

Long Term Storage:	-20°C

Scientific Background:	Aurora A, B, and C have emerged as key mitotic regulators of mammalian centrosome function, chromosome segregation and cytokinesis. Aurora B is one of several chromosomal passenger proteins involved in chromosome alignment at the metaphase plate and cytokinesis. Phosphorylation of a threonine residue in the Aurora activation loop (Thr232 in human Aurora B) is believed to be an essential regulatory mechanism in Aurora kinase activation.

Regulatory Status:	RUO - Research Use Only