| ADI-AGR-530-D | 50 µg | 269.00 USD |  |
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| ADI-AGR-530-F | 200 µg | 515.00 USD | |
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| Clone: | Agr-131 |
| Host: | Mouse |
| Isotype: | IgG2a |
| Immunogen: | Recombinant rat agrin (C-terminal fragment). |
| UniProt ID: | P25304 |
| GenBank ID: | M64780 |
| Source: | Purified from mouse ascites. |
| Species reactivity: | Mouse, Rat |
| Applications: | ICC, IHC (PS), WB Microarray |
| Recommended Dilutions/Conditions: | Western Blot (1:1,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~100kDa by Western blot. |
| Purity Detail: | Protein G affinity purified. |
| Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins at the neuromuscular junction during development. Agrin, MuSK, and Rapsyn are all essential components for AChR aggregation, through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface and induces AChR aggregation. |
| Regulatory Status: | RUO - Research Use Only |
Goat anti-mouse IgG F(ab')2, polyclonal antibody (HRP conjugate) |
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| ELISA, IHC, WB | Print as PDF | ||||||
| ADI-SAB-100-J | 1 ml | 154.00 USD | |
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Goat anti-mouse IgG, polyclonal antibody (AP conjugate) |
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| ELISA, WB | Print as PDF | ||||||
| ADI-SAB-101-J | 1 ml | 175.00 USD | |
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