| ADI-908-305-0010 | 10 µg | Inquire for pricing | |||
| Do you need bulk/larger quantities? | |||||
| Alternative Name: | KLK6, Neurosin, Protease M |
| MW: | ~27kDa |
| Source: | Produced in insect cells. Human recombinant KLK6 (aa 17-244) is fused to a His-tag. Produced in a baculovirus expression system. |
| EC: | 3.4.21.- |
| UniProt ID: | Q92876 |
| GenBank ID: | 30582543 |
| Formulation: | Liquid. In 1X PBS. |
| Purity: | ≥90% (SDS-PAGE) |
| Applications: | ELISA, WB |
| Application Notes: | Western blot control. |
| Solubility: | Soluble in 1X PBS or water |
| Shipping: | Blue Ice |
| Short Term Storage: | +4°C |
| Long Term Storage: | -20°C |
| Handling: | Avoid freeze/thaw cycles. |
| Scientific Background: | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins, including KLK6, are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded KLK6 enzyme is regulated by steroid hormones. In tissue culture, KLK6 has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. |
| Regulatory Status: | RUO - Research Use Only |
