| Clone: | 1B2F2 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Recombinant human LSD1 truncated protein. |
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| UniProt ID: | O60341 |
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| Source: | Purified from mouse ascites. |
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| Species reactivity: | Human, Mouse, Rat
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| Applications: | WB
|
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| Purity Detail: | Protein G affinity purified. |
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| Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | Lysine-specific demethylase 1 (LSD1, AOF2, BHC110) is a nuclear amine oxidase homolog, and was the first such protein to display definitive activity in epigenetic modulation as a histone demethylase. LSD1 demethylates histone H3 at mono- or di-methylated lysine residues. Depending on associated co-factors, LSD1-mediated demethylation can lead to transcriptional repression or activation. |
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| Regulatory Status: | RUO - Research Use Only |
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