| Clone: | 43AT551.86.76 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Recombinant human SET07 (N-terminal fragment). |
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| UniProt ID: | Q8WTS6 |
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| Species reactivity: | Human, Mouse
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| Applications: | ELISA, WB
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| Recommended Dilutions/Conditions: | ELISA (1:1,000)
Western Blot (1:100-1:500)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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| Purity Detail: | Peptide affinity purified. |
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| Formulation: | Liquid. In PBS containing 0.09% sodium azide. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | SET07 is a histone methyltransferase that methylates Lys20 of histone H4, a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of the H4 tail. |
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| Regulatory Status: | RUO - Research Use Only |
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