| ADI-905-643-100 | 100 µg | 556.00 USD |  |
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| Alternative Name: | Insulin-like growth factor-1 receptor, IGF-1R |
| Clone: | 2B9 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | Synthetic peptide corresponding to a portion of human IGF-1 receptor phosphorylated at Tyr1316. |
| UniProt ID: | P08069 |
| Species reactivity: | Human |
| Applications: | ELISA, WB |
| Recommended Dilutions/Conditions: | ELISA (0.1µg/ml) Western Blot (1µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~97kDa by Western blot. |
| Purity Detail: | Thiophilic adsorption and size exclusion chromatography purified. |
| Formulation: | Lyophilized from 1ml of 2x PBS containing 0.09% sodium azide, PEG, and sucrose. |
| Reconstitution: | Reconstitute with 1ml water (15 minutes at room temperature). |
| Use/Stability: | Stable at -80°C up to 1 year, at 4°C up to 3 months. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Insulin-like growth factor-I (IGF-I) is a polypeptide hormone similar in structure to insulin. It is involved in regulation of neuronal growth and development in the central and peripheral nervous system. IGF-1 is a potent inhibitor of apoptosis in neurons, and activates the Akt signaling pathway via the IGF-1R and Insulin receptors. The IGF-1R acts as a receptor for IGF-1 and the related IGF-2, and is subject to autophosphorylation on multiple tyrosine residues that regulate receptor activation and assembly of signal transduction complexes. |
| Regulatory Status: | RUO - Research Use Only |
![[pTyr1316]IGF-1 receptor monoclonal antibody (2B9) Western blot](https://www.enzolifesciences.com/fileadmin/files/image/905-643_WB.jpg "[pTyr1316]IGF-1 receptor monoclonal antibody (2B9) Western blot")
![[pTyr1316]IGF-1 receptor monoclonal antibody (2B9) Western blot](https://www.enzolifesciences.com/fileadmin/thumbs/2b4c75831fe804a8c84e47d2a15161c807c418a1-905-643_WB.jpg.jpg "[pTyr1316]IGF-1 receptor monoclonal antibody (2B9) Western blot")
