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Easy-to-use - ready-to-use liquid color-coded reagents reduce errors
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Reliable - reproducible results day-after-day and lot-after-lot
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Fast - results in just 2 hours from up to 39 samples in duplicate
The COX-2 (human), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 2 hours.
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Product Details
| Alternative Name: | Cyclooxygenase-2, Prostaglandin H synthase 2 |
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| Sensitivity: | 0.25 ng/ml (range 1.09 - 70 ng/ml) |
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| Assay Time: | 2 hours |
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| Applications: | ELISA, Colorimetric detection
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| Application Notes: | For the quantitative determination of human COX-2 in cell lysates. |
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| Wavelength: | 450 nm |
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| Species reactivity: | Human
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| Crossreactivity: | Human COX-2 (100%), human COX-1 (<0.1%) |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Contents: | Microtiter plate, Labeled antibody concentrate, Antibody diluent, Assay buffer, Wash buffer concentrate, Standard, TMB Substrate, Stop solution |
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| Scientific Background: | Cyclooxygenases-1 and 2 (COX-1 and COX-2) also known as Prostaglandin endoperoxide H synthases-1 and 2 are integral membrane proteins which catalyze the first step of prostaglandin, thromboxane, and prostacyclin production from arachidonic acid. The COX-1 and COX-2 enzymes are important pharmacologically as targets of nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin, ibuprofen and the COX-2 inhibitors. Inhibition of cyclooxygenases with NSAIDs acutely reduces inflammation, pain, and fever. |
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| UniProt ID: | P35354 |
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| Regulatory Status: | RUO - Research Use Only |
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| Compatibility: | This product is compatible with the Absorbance 96 Plate Reader.
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Product Literature References
Exploring the therapeutic efficacy of Chlorella pyrenoidosa peptides in ameliorating Alzheimer’s disease: S.M. Wang, et al.; Heliyon
9, e15406 (2023),
Abstract;
Mechanism of the anti-angiogenic effect of avemar on tumor cells: N.G. Imir, et al.; Oncol. Lett.
15, 2673 (2018),
Application(s): ELISA using cell lysates,
Abstract;
Full Text
Anti-Inflammatory Activity of Haskap Cultivars is Polyphenols-Dependent: H.P. Vasantha Rupasinghe, et al.; Biomolecules
5, 1079 (2015),
Application(s): ELISA using human leukemia monocytes ,
Abstract;
Full Text
Docosahexaenoic acid ester of phloridzin inhibit lipopolysaccharide-induced inflammation in THP-1 differentiated macrophages: S. Sekhon-Loodu, et al.; Int. Immunopharmacol.
25, 199 (2015),
Application(s): ELISA,
Abstract;
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