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Stem Cell Differentiation

Modulate Stem Cell Fate with Small Molecules & Proteins

Stem cell self-renewal and differentiation involves complex events which lead to the generation of various phenotypes. Enzo offers an extensive collection of small molecules and proteins such as growth factors and cytokines that can be used to influence differentiation, biochemical activity, and cell growth.

Featured product

Noggin (human), (recombinant)

Noggin is essential for cartilage morphogenesis and joint formation. Its involved in the development of many body tissues, including nerve tissue, muscles, and bones. Noggin binds and inactivates members of the transforming growth factor-beta (TGF-β) superfamily proteins, such as bone morphogenetic protein (BMP4). BMP signaling is required for growth and patterning of the neural tube and somite.

Brochures
Stem Cells
 

Small Molecules

Differentiation

Compound E 

γ-Secretase inhibitor
209986-17-4, ≥95% (HPLC) | Print as PDF
 
ALX-270-415-C250 250 µg 124.00 USD
 
ALX-270-415-M001 1 mg 353.00 USD
Do you need bulk/larger quantities?
 

Cyclopamine 

Blocks Hedgehog signaling
4449-51-8, ≥98% (TLC) | Print as PDF
 
BML-GR334-0001 1 mg 116.00 USD
 
BML-GR334-0005 5 mg 468.00 USD
Do you need bulk/larger quantities?
 

DAPT 

γ-Secretase inhibitor
208255-80-5, ≥98% (HPLC) | Print as PDF
 
ALX-270-416-M005 5 mg 104.00 USD
 
ALX-270-416-M025 25 mg 377.00 USD
Do you need bulk/larger quantities?
 

Dexamethasone 

Glucocorticoid receptor ligand
50-02-2, ≥98% (HPLC) | Print as PDF
 
BML-EI126-0001 1 g 71.00 USD
 
BML-EI126-0005 5 g 283.00 USD
Do you need bulk/larger quantities?
 

DIF-1 

Ultra-pure; Induces cell differentiation
111050-72-7, ≥98% (HPLC) | Print as PDF
 
BML-GR324-0100 100 µg 71.00 USD
 
BML-GR324-0500 500 µg 289.00 USD
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Forskolin 

Adenylate cyclase activator
66575-29-9, Isolated from Coleus forskohlii., ≥97% (HPLC, TLC) | Print as PDF
 
BML-CN100-0010 10 mg 123.00 USD
 
BML-CN100-0100 100 mg 736.00 USD
Do you need bulk/larger quantities?
 

IDE-1 

Induces stem cell differentiation
1160927-48-9, ≥99% (HPLC) | Print as PDF
 
BML-SC100-0001 1 mg 114.00 USD
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IDE-2 

Induces stem cell differentiation
1136466-93-7, ≥98% (TLC) | Print as PDF
 
BML-SC101-0001 1 mg 117.00 USD
 
BML-SC101-0005 5 mg 359.00 USD
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Purmorphamine 

Smoothened activator
483367-10-8, ≥98% (HPLC) | Print as PDF
 
ALX-420-045-M001 1 mg 57.00 USD
 
ALX-420-045-M005 5 mg 191.00 USD
 
ALX-420-045-M025 25 mg 625.00 USD
Do you need bulk/larger quantities?
 

Retinoic acid, all trans 

Retinoic acid receptor ligand
302-79-4, ≥95% | Print as PDF
 
BML-GR100-0500 500 mg 66.00 USD
 
BML-GR100-5000 5 g 347.00 USD
Do you need bulk/larger quantities?
 

Sodium butyrate 

HDAC inhibitor. Apoptosis inducer.
156-54-7, ≥95% (HPLC) | Print as PDF
 
ALX-270-301-G001 1 g 152.00 USD
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Valproic acid . sodium salt 

Anticonvulsant and anti-depressant
1069-66-5, ≥98% (GC) | Print as PDF
 
ALX-550-304-G005 5 g 37.00 USD
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Proliferation & Self-Renewal

BI-D1870 

S6 kinase inhibitor
501437-28-1, ≥98% (HPLC) | Print as PDF
 
BML-EI407-0001 1 mg 72.00 USD
 
BML-EI407-0005 5 mg 208.00 USD
Do you need bulk/larger quantities?
 

BML-275 

AMPK inhibitor
866405-64-3, ≥98% (TLC) | Print as PDF
 
BML-EI369-0005 5 mg 93.00 USD
 
BML-EI369-0025 25 mg 375.00 USD
Do you need bulk/larger quantities?
 

ID-8 

Enables the long-term expansion of embryonic stem cells
147591-46-6, ≥98% | Print as PDF
 
BML-SC105-0005 5 mg 69.00 USD
 
BML-SC105-0025 25 mg 284.00 USD
Do you need bulk/larger quantities?
 

XAV939 

PARP5a inhibitor
284028-89-3, ≥98% (HPLC) | Print as PDF
 
BML-WN100-0005 5 mg 59.00 USD
 
BML-WN100-0025 25 mg 226.00 USD
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Y-27632 . dihydrochloride 

ROCK inhibitor
129830-38-2, ≥98% (HPLC (UV)) | Print as PDF
 
ALX-270-333-M001 1 mg 90.00 USD
 
ALX-270-333-M005 5 mg 182.00 USD
 
ALX-270-333-M025 25 mg 571.00 USD
Do you need bulk/larger quantities?
 

Re-programming

ALK5 Inhibitor I 

396129-53-6, ≥97% (1H-NMR) | Print as PDF
 
ALX-270-448-M001 1 mg 71.00 USD
 
ALX-270-448-M005 5 mg 104.00 USD
Do you need bulk/larger quantities?
 

AM-580 

Retinoic acid receptor ligand
102121-60-8, ≥98% (TLC) | Print as PDF
 
BML-GR104-0005 5 mg 100.00 USD
 
BML-GR104-0025 25 mg 417.00 USD
Do you need bulk/larger quantities?
 

Doxycycline . hyclate 

MMP inhibitor
24390-14-5, Semisynthetic from oxytetracycline., ≥98% (HPLC) | Print as PDF
 
ALX-380-273-G001 1 g 37.00 USD
 
ALX-380-273-G005 5 g 77.00 USD
Do you need bulk/larger quantities?
 

Pifithrin-α (cyclic) . hydrobromide 

p53 inhibitor
60477-34-1, ≥95% (HPLC, TLC) | Print as PDF
 
ALX-270-287-M010 10 mg 171.00 USD
 
ALX-270-287-M050 50 mg 706.00 USD
Do you need bulk/larger quantities?
 

Pifithrin-α 

p53 inhibitor
63208-82-2, ≥98% (TLC) | Print as PDF
 
BML-GR325-0005 5 mg 79.00 USD
 
BML-GR325-0025 25 mg 333.00 USD
Do you need bulk/larger quantities?
 

Pifithrin μ 

HSP70 inhibitor
64984-31-2, ≥98% (TLC) | Print as PDF
 
BML-AP503-0005 5 mg 58.00 USD
 
BML-AP503-0025 25 mg 183.00 USD
Do you need bulk/larger quantities?
 

Tranylcypromine 

Demethylase inhibitor
13492-01-8, ≥98% (HPLC) | Print as PDF
 
BML-EI217-0001 1 g 114.00 USD
 
BML-EI217-0005 5 g 458.00 USD
Do you need bulk/larger quantities?
 

Compound Libraries

SCREEN-WELL® Cardiotoxicity library 

Essential standards for predictive toxicology screening
HTS | Print as PDF
 
BML-2850-0500 1 Library 500 µl/well Inquire for pricing
 
BML-2850-0100 1 Library 100 µl/well Inquire for pricing
Do you need bulk/larger quantities?
 

SCREEN-WELL® Hepatotoxicity library 

Essential standards for predictive toxicology screening
HTS | Print as PDF
 
BML-2851-0500 1 Library 500 µl/well Inquire for pricing
 
BML-2851-0100 1 Library 100 µl/well Inquire for pricing
Do you need bulk/larger quantities?
 

SCREEN-WELL® Hematopoietic Toxicity library 

Essential standards for predictive toxicology screening
HTS | Print as PDF
 
BML-2852-0500 1 Library 500 µl/well Inquire for pricing
 
BML-2852-0100 1 Library 100 µl/well Inquire for pricing
Do you need bulk/larger quantities?
 

SCREEN-WELL® Wnt Pathway library 

Compounds are highly relevant; many are unique
HTS | Print as PDF
 
BML-2838-0500 1 Library 500 µl/well Inquire for pricing
 
BML-2838-0100 1 Library 100 µl/well Inquire for pricing
Do you need bulk/larger quantities?
 

SCREEN-WELL® Epigenetics library 

HTS | Print as PDF
 
BML-2836-0500 1 Library 500 µl/well Inquire for pricing
 
BML-2836-0100 1 Library 100 µl/well Inquire for pricing
Do you need bulk/larger quantities?
 

SCREEN-WELL® FDA approved drug library V2 

Accelerates drug optimization with a unique collection of compounds of known safety and bioavailability for diverse targets.
HTS | Print as PDF
 
BML-2843-0100 1 Library 100 µl/well Inquire for pricing
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Proteins

Growth Factors

Flt-3 ligand (human), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 155 amino acids., ≥95% (Reducing and Non-reducing SDS-PAGE) | Print as PDF
 
ALX-201-800-0002 2 µg 145.00 USD
 
ALX-201-800-0010 10 µg 244.00 USD
 
ALX-201-800-0100 100 µg 862.00 USD
Do you need bulk/larger quantities?
 

Flt-3 ligand (mouse), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 163 amino acids., ≥98% (Reducing and Non-reducing SDS-PAGE) | Print as PDF
 
ALX-201-801-0002 2 µg 145.00 USD
 
ALX-201-801-0010 10 µg 244.00 USD
 
ALX-201-801-0100 100 µg 862.00 USD
Do you need bulk/larger quantities?
 

GM-CSF (mouse), (recombinant) 

Produced in E. coli., ≥99% (RP-HPLC; Anion-exchange FPLC; Reducing and non-reducing SDS-PAGE), in vitro Assay | Print as PDF
 
ADI-908-064-005 5 µg 170.00 USD
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Growth and differentiation factor-5 (human), (recombinant) 

Produced in E. coli. Non-glycosylated homodimer, containing two 117 amino acids chains. To enable bacterial expression the N-terminal sequence of Ala-Pro-Leu-Thr was replaced with a Lys., ≥98% (HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-802-0010 10 µg 145.00 USD
 
ALX-201-802-0050 50 µg 244.00 USD
 
ALX-201-802-0100 100 µg 450.00 USD
Do you need bulk/larger quantities?
 

Growth and differentiation factor-15 (human), (recombinant) 

Produced in E. coli. Non-glycosylated, disulfide linked homodimer, containing two identical 113 amino acid chains., ≥95% (HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-803-0005 5 µg 145.00 USD
 
ALX-201-803-0020 20 µg 244.00 USD
 
ALX-201-803-0100 100 µg 882.00 USD
Do you need bulk/larger quantities?
 

Stem cell factor (human), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 165 amino acids., ≥98% (Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-804-0002 2 µg 145.00 USD
 
ALX-201-804-0010 10 µg 242.00 USD
 
ALX-201-804-0100 100 µg 780.00 USD
Do you need bulk/larger quantities?
 

Stem cell factor (mouse), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 164 amino acids., ≥95% (reducing and non-reducing SDS-PAGE) | Print as PDF
 
ALX-201-805-0002 2 µg 145.00 USD
 
ALX-201-805-0010 10 µg 225.00 USD
 
ALX-201-805-0100 100 µg 780.00 USD
Do you need bulk/larger quantities?
 

Stem cell factor (rat), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 165 amino acids., ≥98% (Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-806-0002 2 µg 145.00 USD
 
ALX-201-806-0010 10 µg 244.00 USD
 
ALX-201-806-0100 100 µg 780.00 USD
Do you need bulk/larger quantities?
 

Thrombopoietin (mouse), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 174 amino acids (which comprise the receptor binding domain)., ≥95% (Reducing and Non-reducing SDS-PAGE) | Print as PDF
 
ALX-201-808-0002 2 µg 145.00 USD
 
ALX-201-808-0010 10 µg 244.00 USD
 
ALX-201-808-0100 100 µg 940.00 USD
Do you need bulk/larger quantities?
 

Activin-A (human), (recombinant) 

Produced in E. coli. Non-glycosylated homodimer, containing two 117 amino acid chains., ≥95% (HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-809-0010 10 µg 246.00 USD
 
ALX-201-809-0100 100 µg 800.00 USD
Do you need bulk/larger quantities?
 

Epidermal growth factor (rat), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 54 amino acids, with a molecular weight of 6.3 kDa., ≥95% (HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-812-0100 100 µg 244.00 USD
Do you need bulk/larger quantities?
 

Follistatin (human), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 289 amino acids., ≥95% (HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-813-0020 20 µg 246.00 USD
 
ALX-201-813-0100 100 µg 800.00 USD
Do you need bulk/larger quantities?
 

Follistatin (mouse), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 289 amino acids., ≥90% (Reducing and Non-reducing SDS-PAGE) | Print as PDF
 
ALX-201-814-0020 20 µg 242.00 USD
Do you need bulk/larger quantities?
 

Dkk-1 (mouse), (recombinant) (His-tag) 

Produced in E. coli. Mouse Dkk-1 is fused at the N-terminus to a His-tag., ≥95% (SDS-PAGE; Western blot), WB | Print as PDF
 
ADI-KPR-CP100-D 50 µg 365.00 USD
 
ADI-KPR-CP100-F 200 µg 987.00 USD
Do you need bulk/larger quantities?
 

Wnt-3a (mouse), (recombinant) 

Modulator of embryogenesis, cell proliferation, stem cell differentation, and bone, glucose and lipid metabolism
Cell culture, >75% by SDS-PAGE and >75% by HPLC analyses | Print as PDF
 
ENZ-60001-C001 1 µg 164.00 USD
Do you need bulk/larger quantities?
 

Galanin (human) 

Neuropeptide
119418-04-1, ≥98% | Print as PDF
 
ALX-157-003-P001 1 mg* 366.00 USD
Do you need bulk/larger quantities?
 

Cytokines/Chemokines

IL-12 (mouse), (recombinant) 

Produced in HEK293 cells. Glycosylated, disulfide-linked heterodimer. It contains one p35 subunit (35 kDa) and one p40 subunit (40 kDa), with a total of 506 amino acids., ≥95% (Reducing and Non-reducing SDS-PAGE) | Print as PDF
 
ALX-201-815-0010 10 µg 242.00 USD
 
ALX-201-815-0100 100 µg 1,601.00 USD
Do you need bulk/larger quantities?
 

TARC (human), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 71 amino acids., ≥98% (HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-816-0020 20 µg 244.00 USD
 
ALX-201-816-0100 100 µg 800.00 USD
Do you need bulk/larger quantities?
 

TGF-β3 (mouse), (recombinant) 

Produced in E. coli. Non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains., ≥98% (Reducing and Non-reducing SDS-PAGE) | Print as PDF
 
ALX-201-817-0010 10 µg 225.00 USD
 
ALX-201-817-0100 100 µg 752.00 USD
Do you need bulk/larger quantities?
 

IL-6 (human), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 184 amino acids., ≥95% (Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-818-0020 20 µg 215.00 USD
 
ALX-201-818-0100 100 µg 780.00 USD
Do you need bulk/larger quantities?
 

IL-6 (mouse), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 187 amino acids., ≥95% (HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-819-0010 10 µg 215.00 USD
 
ALX-201-819-0100 100 µg 917.00 USD
Do you need bulk/larger quantities?
 

IL-3 (human), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 134 amino acids., ≥95% (Reducing and Non-reducing SDS-PAGE) | Print as PDF
 
ALX-201-820-0010 10 µg 246.00 USD
 
ALX-201-820-0100 100 µg 780.00 USD
Do you need bulk/larger quantities?
 

IL-3 (mouse), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 135 amino acids., ≥95% (reducing and non-reducing SDS-PAGE) | Print as PDF
 
ALX-201-821-0010 10 µg 215.00 USD
 
ALX-201-821-0100 100 µg 940.00 USD
Do you need bulk/larger quantities?
 

FGF-basic 147 (human), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 147 amino acids., ≥95% (Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-822-0010 10 µg 145.00 USD
 
ALX-201-822-0050 50 µg 242.00 USD
 
ALX-201-822-0100 100 µg 680.00 USD
Do you need bulk/larger quantities?
 

FGF-basic 154 (human), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 154 amino acids., ≥97% (Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm) | Print as PDF
 
ALX-201-823-0010 10 µg 145.00 USD
 
ALX-201-823-0050 50 µg 215.00 USD
 
ALX-201-823-0100 100 µg 625.00 USD
Do you need bulk/larger quantities?
 

FGF basic (mouse), (recombinant) 

Produced in E. coli. Non-glycosylated protein, containing 145 amino acids., ≥95% (Reducing and Non-reducing SDS-PAGE) | Print as PDF
 
ALX-201-824-0010 10 µg 145.00 USD
 
ALX-201-824-0050 50 µg 244.00 USD
 
ALX-201-824-0100 100 µg 680.00 USD
Do you need bulk/larger quantities?
 

Stem Cell Markers

Thy-1 (human):Fc (human), (recombinant) 

Produced in HEK 293 cells. The extracellular domain of human Thy-1 (aa 20-130) is fused to the Fc portion of human IgG1., ≥90% (SDS-PAGE) | Print as PDF
 
ALX-522-091-C050 50 µg 453.00 USD
Do you need bulk/larger quantities?
 
 
 
 

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