Stress & Heat Shock Proteins

The highly conserved heat shock proteins (HSPs) are constitutively expressed and function as molecular chaperones which facilitate the synthesis and folding of proteins. They also participate in protein assembly, export, turn-over and regulation. Under stressful conditions such as heat shock, pH shift or hypoxia, increased expression of HSPs protect the cell by stabilizing unfolded proteins, giving the cell time to repair or re-synthesize damaged proteins. ELS offers a number of kits (and antibodies, proteins, inhibitors, etc.) to study HSPs/chaperones, HSF’s, Grp’s, ERp’s, clusterin and other stress related molecules.