Protein Expression & Modification

Protein synthesis, folding, and post-translational modifications are of vital importance in proteomic studies of biological systems. Evaluation of protein homeostasis (proteostasis) extends beyond translation to involve assisted folding by molecular chaperones and chemical modification to achieve a protein’s native conformation. Further, a multitude of chemical modifications (e.g. phosphorylation, ubiquitinylation, acetylation, glycosylation, SUMOylation, and methylation) are utilized to regulate proper localization and function. Enzo Life Sciences’ extensive range of chaperone and post-translational modification reagents facilitates detailed characterization of these mechanisms of proteostasis.