Predictive Toxicology

The drug development industry has undertaken significant efforts to identify toxic events at the earliest opportunity during the development process, moving from a predominantly observational science at the level of disease-specific models to a more predictive model focused on target-specific, mechanism-based biological observations. The growth in such Early Safety Assessment initiatives has driven the need for more reliable, cost-effective high throughput in vitro toxicity assays capable of predicting toxic liabilities prior to investment in more costly pre-clinical and clinical trials.

Through our broad range of scientific expertise and industry-proven manufacturing capabilities, Enzo Life Sciences provides a comprehensive set of solutions for the toxicology market, including cell based assays, focused compound libraries, as well as assay kits and reagents for biomarker detection and pathway analysis.

The ABCs and HSPs of Breast Cancer: Researchers Target MDR and Stress Proteins to Reverse Chemoresistance and Cardiotoxicity.
2013 March 15 | Tags: Cancer, Toxicology

Nobel Prize Winners Experience GPCR-Mediated Adrenaline Rush.
2013 February 1 | Tags: Drug Discovery, Screening, Toxicology

Circumventing drug resistance in breast cancer cells by down-regulating the Wnt/β-catenin pathway.
2012 November 16 | Tags: Cancer, Screening, Toxicology