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Pathogene® & BioProbe® Virus Detection Assays

PathoGene® Human Papillomavirus in situ typing assays for sensitive detection of pathogen-expressed genes from fresh or FFPE tissue sections

The assays employ separate mixtures of biotin-labeled Human Papillomavirus (HPV)-specific probes to detect and identify HPV/DNA-infected biopsy tissue sections. The identifying probes are HPV types 6/11 (benign lesions), 16/18 (cervical intraepithelial neoplasia [CIN] and carcinoma in situ [CIS]), or 31/33/51 (condyloma or cervical intraepithelial neoplasia [CIN] and carcinoma in situ [CIS]).

  • Provides all reagents and materials for preparation and pretreatment as well as hybridization/detection and typing of HPV DNA.
  • Suitable for processing paraffin-embedded tissue manually or on automated slides-stainers.
  • HPV 16 Probe Control Slide is available separately to serve as a positive control for HPV-16 DNA detection.

Detect and Identify HPV Infection In Situ

CIN/condylomata biopsy specimen infected with HPV type 16 DNA. The HPV 16/18 Probe Reagent exhibited strong nuclear staining Tissue sections were developed with (A) HRP-AEC (100X) and (B) HRP-DAB (400X) and counterstained with hematoxylin.

References:

  1. Brown DR, et. al. Neutralization of human papillomavirus type 11 (HPV-11) by serum from women vaccinated with yeast-derived HPV-11 L1 virus-like particles: correlation with competitive radioimmunoassay titer.J Infect Dis. 2001 Nov 1;184(9):1183-6.
  2. Lajer CB, et. al. Different miRNA signatures of oral and pharyngeal squamous cell carcinomas: a prospective translational study. Br J Cancer. 2011 Mar 1;104(5):830-40.
  3. Nuovo GJ, et. al. Strong inverse correlation between microRNA-125b and human papillomavirus DNA in productive infection. Diagn Mol Pathol. 2010 Sep;19(3):135-43.

Pathogene® HPV Probes & Detection Assays

PathoGene® Alk phos-NBT/BCIP human papillomavirus in situ typing assay for tissue sections (types 6/11, 16/18 and 31/33/51) 

Colorimetric detection | Print as PDF
 
ENZ-32895 10 assays 1,350.00 USD
 

PathoGene® Hrp-AEC human papillomavirus in situ typing assay for tissue sections (types 6/11, 16/18 and 31/33/51) 

Colorimetric detection | Print as PDF
 
ENZ-32877 20 assays 2,380.00 USD
 

PathoGene® Hrp-DAB human papillomavirus in situ typing assay for tissue sections (types 6/11, 16/18 and 31/33/51) 

Colorimetric detection | Print as PDF
 
ENZ-32874 20 assays 2,300.00 USD
 

PathoGene® Human papillomavirus in situ screening assay for tissue sections 

Colorimetric detection | Print as PDF
 
ENZ-32879 20 assays 1,275.00 USD
 

HPV 16 control slide 

Print as PDF
 
ENZ-31877 1 Slide 54.00 USD
 

PathoGene® HPV type 6/11 probe 

Print as PDF
 
ENZ-32885-6000 6 ml INQUIRE
 
ENZ-32885 1 ml 800.00 USD
 

PathoGene® HPV type 16/18 probe 

Print as PDF
 
ENZ-32886-6000 6 ml INQUIRE
 
ENZ-32886 1 ml 500.00 USD
 

PathoGene® HPV type 31/33/51 probe 

Print as PDF
 
ENZ-32887-6000 6 ml INQUIRE
 
ENZ-32887 1 ml 500.00 USD
 

BioProbe® Infectious Agent Probes

Adenovirus BioProbe® 

Print as PDF
 
ENZ-40834 2 µg 260.00 USD
 

Cytomegalovirus BioProbe® 

Print as PDF
 
ENZ-40835 2 µg 260.00 USD
 

Herpes simplex virus BioProbe® 

Print as PDF
 
ENZ-40838 2 µg 265.00 USD
 

Hepatitis A virus BioProbe® 

Print as PDF
 
ENZ-40842 2 µg 242.00 USD
 

SV40 BioProbe® 

Print as PDF
 
ENZ-40845 2 µg 258.00 USD
 

JC virus BioProbe® 

Print as PDF
 
ENZ-40847 2 µg 260.00 USD
 

BK virus BioProbe® 

Print as PDF
 
ENZ-40848 2 µg 258.00 USD
 

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