Genomics & Molecular Biology

Clear Results With Innovative Nucleic Acid Labeling

Enzo Life Sciences is a recognized pioneer and innovator of life sciences tools, backed by patented DNA and RNA labeling chemistries for genomics research and development. The pillar of our molecular biology portfolio is our array-based comparative genomic hybridization (aCGH) kit, a powerful platform for detecting DNA copy number gains and losses associated with chromosome abnormalities. aCGH provides a greater understanding and characterization of genetic disorders, cancers, and other genomic aberrations.

Supporting our aCGH kits are a variety of every day-use molecular biology products designed to maximize the quantity and quality of data generated from your valuable samples. These include RNA and DNA amplification kits, as well as labeling systems and modified nucleotides designed for creating biotin- or fluorophore-labeled nucleic acid probes for a variety of applications and detection platforms. The products have been specifically designed to provide optimal performance in nick translation reactions or with microarrays.

Our panel of PathoGene® kits provides high-specificity probes used to classify human papillomavirus (HPV) genotypes in tissue sections by in situ hybridization. Flexible SimplySensitive® and UltraSensitive® detection systems are optimized for use with biotin labeled probes for in situ detection of specific endogenous or pathogen-expressed genes.

Cellular responses to DNA damage constitute one of the most important fields in cancer biology. DNA damage kits are fast and sensitive assays that monitor response to reactive oxygen species (ROS) and their impact on nucleotide bases and single- and double-stranded DNA breaks.