Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Cardiovascular





Discover, Analyze, Quantify Cardiovascular Biomarkers

Tools For Discovery & Detection of Cardiac Disease Markers

The cardiovascular or circulatory system provides the body with essential nutrients and oxygen. Besides its nourishing function, it also plays a crucial role in inflammation and fighting infections, maintaining homeostasis, transporting hormones, and stabilizing body temperature. It also assists the body in recovering from damage and trauma. Although the system is extremely resilient, repeated or continuous stress can cause long-term damage and lead to cardiovascular diseases such as heart failure and stroke.

Cardiovascular disease is consistently ranked as the single largest cause of death in the world, and it may be caused by heart damage or vascular problems. Challenges in cardiovascular clinical development have caused researchers to take a closer look at cardiac function and metabolism. Enzo Life Sciences offers a comprehensive portfolio of products to enable discovery of cardiac risk factors as well as analysis of the cellular response to novel therapeutics for cardiovascular medicine.

Latest Literature

Product Flyers
Discover, Analyze & Quantify Cardiovascular Biomarkers
Discover, Analyze & Quantify Cardiovascular Biomarkers 20-Mar-14
Download as PDF
 

Pump Up Your Research

 

Vascular Biology

Evaluate Vascular Growth, Inflammatory Responses And Coagulation

A complete portfolio of assays, enzymes and compounds to study vascular development, regulation and disease

 

Vascular Growth And Maintenance

ELISAs, Activity Assays and Abs for monitoring vascular changes such as clotting, fibrinolysis, and angiogenesis.

Vascular Growth And Maintenance

Inflammation And Disease

Accurate quantification for inflammatory compounds which play a role to vascular disease

  • PGE2 Immunoassays
  • Cytokine ELISAs
  • Markers for Vascular Disesase: FABP4, Haptoglobin, Adiponectin
Inflammation And Disease
 

Cardiac Function

A full range of antibodies, detection and activity assays for the reliable detection of cardiac disease biomarkers.

 

Monitor Calcium Mobilization

A Brighter, More Robust Fluorescent Assay for Calcium Mobilization
Intracellular calcium mobilization is critical to maintaining cellular depolarization during ventricular contraction. Enzo FluoForte dyes are optimized for high-throughput detection of intracellular calcium in living cells such as cardiomyocytes.

Monitor Calcium Mobilization

Screen For Inhibitors Of Phosphatase

Highly Cited Assay for Detection of Calcineurin Activity in Cardiac Myocytes
Calcineurin, a protein phosphatase involved in immune cell signaling, is a target for inhibitors such as everolimus which are used in heart transplantation to prevent rejection.

Screen For Inhibitors Of Phosphatase

Detect Markers of Myocardial Infarction

Highly specific, validated antibodies for natriuretic peptide detection
The brain natriuretic peptide (BNP) and atrial natriuretic peptide (ANP) are synthesized in cardiomyocytes in response to various forms of stress, and have a powerful vasodilatory effect. In clinical settings, normal levels of BNP and ANP can be used to rule out myocardial infarction.

Detect Markers of Myocardial Infarction

Evaluation of Cardiac Disease States

A full range of antibodies, detection and activity assays for the reliable detection of cardiac disease biomarkers.

 

Cardiac Injury

Most Sensitive ELISA for Detection of Troponin I
Troponin I is an inhibitory troponin subunit that acts in muscle relaxation and which, in its cardiac isoform, is a reliable marker of cardiac injury when identified in elevated levels in the bloodstream.

  • Most sensitive ELISA, detecting as little as 0.38 ng/ml of human troponin
  • Flexible sample types, including: cell lysates, plasma, and serum
  • Simple protocol with results in just 3.5 hours
  • Quantitative results as compared to Western blot analysis
Cardiac Injury

Prevention, Diagnosis & Monitoring

Accurately quantify cardiovascular biomarkers with Enzo’s high sensitivity ELISA kits and antibodies.

Prevention, Diagnosis & Monitoring
 

Vitamin D Deficiency

The Fastest High-Sensitivity Vitamin D ELISA kit
Low levels of vitamin D, an essential secosteroid, has been linked with an increased risk of heart disease and hypertension. Precise measurements of 25-hydroxyvitamin D in serum are critical to identify cardiac risk factors and to prevent vitamin D deficiency. The 25(OH)-Vitamin D assay is quick and accurate, making it the tool of choice for 25(OH)-Vitamin D detection.

Vitamin D Deficiency

Cardiovascular Drug Discovery

Innovative Tools for Profiling Cardiac Toxicity
Screen-Well® Cardiotoxicity Library
A focused collection of 131 compounds with defined and diverse cardiotoxicity. The library includes a variety of structurally and mechanistically different compound classes, as well as nontoxic controls. The compounds are dissolved in DMSO at 10mM and aliquoted into deep-well plates. The library is an essential tool for predictive toxicology screening and assay development.

Cardiovascular Drug Discovery
 

C-Reactive Protein

C-Reactive Protein (CRP) is a pentraxin family protein that is widely used as a biomarker for systemic inflammation and tissue injury. Its primary role in innate immunity is to function as an opsonin for pathogens via activation of the complement pathway and through binding to Fc gamma receptors. CRP has been shown to play an important role in a variety of pathological pathways.

 

CRP, ELISA Kit

  • Sensitive assay detects as little as 12.685 ng/ml in serum and plasma
  • Highly specific with negligible reactivity to other family members
  • Rapid results in just 1.5 hours

Typical standard curve shows broad range of detection

 

Recommend this page

 
Keep in touch

©2014 Enzo Life Sciences, Inc.,