Synthetic peptide with sequence from Ca2+/calmodulin-dependent protein kinase II pseudosubstrate site. Peptide binds calmodulin tightly and inhibits calmodulin-requiring enzymes including CaMKII, phosphodiesterase and calcineurin. IC50=52 nM for CaMKII in the presence of 100 nM calmodulin.
Product Specification
| Alternative Name: | CaMKII (290-309), Ca2+/calmodulin-dependent protein kinase II (290-309), Calmodulin antagonist |
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| MW: | 2274.2 |
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| Purity: | 97% |
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| Sequence: | Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala |
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| CAS: | 115044-69-4 |
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| Long Term Storage: | -20°C |
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| Background / Technical Information: | Please click here for the comprehensive product datasheet. |
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