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ZBP1 (human), pAb (AT133)

[DAI, DNA-dependent activator of IFN-regulatory factors, Z-DNA-binding protein 1, Tumor stroma and activated macrophage protein DLM-1]
 
ALX-210-959-C100 100 µg 350.00 USD
 

Product Specification

Concentration:1mg/ml
 
Purity Detail:Protein A-affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Immunogen:Recombinant human ZBP1 (aa1-429)
 
Source/Host:From rabbit.
 
Specificity:Recognizes human ZBP1.
 
Application:Immunoprecipitation (1:200)
Western blot (1:1’000)
 
Shipping:SHIPPED ON BLUE ICE
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
 
Miscellaneous/General:

ZBP1  is a cytoplasmic recognition receptor that senses and is activated by DNA from several sources. Upon activation, ZBP1 triggers a type I IFN response through the activation of IRF3 and, probably, IRF7.

 

General Literature References

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response A. Takaoka, et al. Nature 448 501 (2007) Abstract

Related Literature

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