ZBP1 (human), pAb (AT133)

Alternative Name:	DAI, DNA-dependent activator of IFN-regulatory factors, Z-DNA-binding protein 1, Tumor stroma and activated macrophage protein DLM-1

Concentration:	1mg/ml

Purity Detail:	Protein A-affinity purified.

Formulation:	Liquid. In PBS containing 0.02% sodium azide.

Immunogen:	Recombinant human ZBP1 (aa1-429)

Source/Host:	From rabbit.

Specificity:	Recognizes human ZBP1.

Application:	Immunoprecipitation (1:200) Western blot (1:1’000)

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Use/Stability:	Stable for at least 1 year after receipt when stored at -20°C.

Handling:	After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Miscellaneous/General:	ZBP1 is a cytoplasmic recognition receptor that senses and is activated by DNA from several sources. Upon activation, ZBP1 triggers a type I IFN response through the activation of IRF3 and, probably, IRF7.