UBE1L (human), pAb



ALX-210-391-R100	100 µl	220.00 USD

Product Specification

Concentration:	~34mg/ml

Formulation:	Liquid. Raw antiserum. Contains no preservatives.

Immunogen:	Synthetic peptide corresponding to aa 222-240 (D²²²CDPRSIHVREDGSLEIGD²⁴⁰) of N-terminal human UBE1L.

Source/Host:	From rabbit.

Specificity:	Recognizes human UBE1L.

Application:	Immunohistochemistry (frozen sections, paraffin sections) Western Blot

Shipping:	SHIPPED ON BLUE ICE

Long Term Storage:	-20°C

Handling:	Avoid freeze/thaw cycles.

Miscellaneous/General:	Human UBE1L shows a 45% homology to the human ubiquitin-activating enzyme E1 at the amino acid level. UBE1L is a retinoid target that triggers promyelocytic leukemia (PML)/ all trans-retinoic acid receptor α (RARα) degradation in acute promyelocytic leukemia.

Product Literature References

UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia: S. Kitareenwan, et al.; PNAS 99, 3806 (2002), Abstract;