Glutathione NEM, mAb (8.IGSH)



ADI-SPA-540-C	25 µg	125.00 USD

ADI-SPA-540-E	100 µg	260.00 USD

Product Specification

Alternative Name:	HAGHL, hydroxyacylglutathione hydrolase-like

Formulation:	Liquid. In PBS, pH 7.2, containing 0.1mM PMSF.

Clone:	8.IGSH

Isotype:	Mouse IgG1

Immunogen:	Thiol-modified glutathione conjugated to KLH.

Specificity:	Recognizes mammals Glutathione NEM.

Application:	ELISA Flow Cytometry Immunocytochemistry Optimal conditions must be determined individually for each application.

Long Term Storage:	-20°C

Miscellaneous/General:	Glutathione, a major intracellular non-protein thiol, protects against free radical damage by providing reducing equivalents for several key antioxidant enzymes. In addition, glutathione acts as a scavenger of hydroxyl radicals and nascent oxygen. Elevated glutathione levels are associated with a reduced rate of illness, higher levels of self-rated health, lower cholesterol, lower body mass index, and lower blood pressure among the elderly. Glutathione provides a primary defense system for the removal of oxidants in the brain. Studies have revealed a correlation between low glutathione levels and damage to neurons that manufacture dopamine, suggesting a link to Parkinson's disease.

Product Literature References

Glutathione distribution in normal and oxidatively stressed cells: D.A. Lawrence, et al. ; Exp. Cell Res. 285, 14 (2003), Application(s): EM using human samples, Abstract;

Phospholipid metabolism of lymphocytes with inhibited glutathione synthesis using L-buthionine-S,R-sulfoximine: D.A. Lawrence, et al. ; Free Radic. Biol. Med. 18, 709 (1995), Application(s): Flow using human samples, Abstract;