Molecular Biology

Gene Expression

DNA microarrays are powerful tools used to detect global changes in gene expression via transcript analysis. Our BioArray® single round RNA Amplification and Labeling system, and cDNA Synthesis kit utilize the “Eberwine method” and provide a convenient all-in-one system that accommodates a wide range of input RNA, with higher yields and highly reproducible results across several microarray platforms.

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CGH Analysis

Comparative Genomic Hybridization (CGH) analysis products are specifically optimized and validated for both BAC and oligonucleotide arrays. Cyanine-3 and Cyanine-5 labeled nucleotides provide superior signal-to-noise ratios on arrays and identify gains or losses in genomic material with greater resolution and reduced variability.

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Nucleic Acid Labeling

A comprehensive portfolio of high quality modified nucleotides and nucleic acid labeling systems accommodate a wide range of applications and detection platforms. Fluorophore labeled nucleotides span the visible light spectrum from blue to red, while Biotin labeled counterparts offer superior affinity for labeled conjugates. Taken together these product lines provide all the necessary tools for in situ hybridization and FISH applications.

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Cytogenetic and Pathogenic Probes

BAC libraries allow for clone selection, characterization, mapping and labeling. When coupled with our family of fluorescent dUTPs, you can create FISH probes utilizing the Nick Translation DNA Labeling System. Additionally, ready-to-use Biotin-labeled PathoGene® Papillomavirus identification systems enable in situ hybridization and detection. SimplySensitive® and UltraSensitive® systems allow the detection of biotin-labeled probes using in situ hybridization methods.

Discover all of our Cytogenetic Probes.