| Alternative Name: | BMP type-1A receptor, Activin receptor-like kinase 3, SKR5 |
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| MW: | Dimer, 40.4/80.8 kDa (362/724 amino acids) |
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| Source: | Produced in genetically modified CHO cells. Contains a C-terminus linker (IEGRMD) and an Fc tag (Human IgG1). |
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| UniProt ID: | P36894 |
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| Formulation: | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing PBS. |
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| Purity: | >95% (SDS-PAGE) |
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| Endotoxin Content: | ≤1 EU/µg |
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| Reconstitution: | Reconstitute in sterile water at 0.1 mg/mL. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -80°C |
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| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution. |
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| Scientific Background: | Bone morphogenetic protein receptor type-1A (BMPR-1A) is a Type I receptor that complexes with BMP Type II receptors to activate SMAD signaling. BMPR-1A is a receptor for BMP-2, BMP-4, GDF-5, and GDF-6. This product contains the first 152 amino acids of the extracellular portion of BMPR-1A and can be used to interfere with or neutralize ligand signaling. |
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| Regulatory Status: | RUO - Research Use Only |
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