Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

PDGF-BB (human), (recombinant)

 
ENZ-PRT257-0100 100 µg 862.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:Platelet-derived growth factor-BB, GDGF, ODGF
 
MW:~12.4/24.9kDa
 
Source:Produced in E. coli. Contains 110/220 amino acids.
 
UniProt ID:P01127
 
Formulation:Lyophilized from a sterile (0.2 micron) filtered solution containing 10 mM sodium phosphate, pH 7.5.
 
Purity:≥95% (SDS-PAGE)
 
Endotoxin Content:≤1 EU/µg protein (LAL test)
 
Reconstitution:Reconstitute in sterile water at 0.1 mg/mL.
 
Shipping:Ambient
 
Long Term Storage:-80°C
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
 
Scientific Background:Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b.
 
ENZ-PRT257
Figure 1: Serial dilutions of Human PDGF-BB, starting at 500 ng/mL, were added to NR-6-R 3T3 cells. Cell proliferation was measured and the linear portion of the curve can be used to calculate the ED50.
Please mouse over
ENZ-PRT257

Related Products

PDGF-AB (human), (recombinant) 

Produced in E. coli. Contains 126, 110/236 amino acids., ≥95% (SDS-PAGE) | Print as PDF
 
ENZ-PRT258-0100 100 µg 862.00 USD
Do you need bulk/larger quantities?
 

PDGF-AA (human), (recombinant) 

Produced in E. coli. Contains 126/252 amino acids., ≥95% (SDS-PAGE) | Print as PDF
 
ENZ-PRT256-0100 100 µg 862.00 USD
Do you need bulk/larger quantities?
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
PDGF
By biological activity:
PDGF Recombinant protein
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2018 Enzo Life Sciences, Inc.,